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XENOTUSS Ex

This combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin is an expectorant.Terbutaline Sulphate is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smooth muscle. Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties.

It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity. Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant.

Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis.

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Guaiphenesin is effective in both productive and nonproductive coughs. Menthol has a cooling effect on the throat. It has been suggested that the benefits of menthol may be due to an effect on calcium channels of sensory nerves.

Indications:
- Productive and unproductive cough
- Cough associated with Upper Respiratory Tract Infections
- Cough due to active and passive smoking
- Allergy
- Asthma

Uses
What is it prescribed for?

Bronchospasm: This medicine is used to relieve the symptoms of bronchospasm such as wheezing, shortness of breath, chest tightness, breathing difficulties, coughing, etc. in patients suffering from conditions such as bronchial asthma, chronic bronchitis, etc

CONCERNS
01.How long does it take for this medicine to take effect?

The effect of this medicine can be observed within 30-45 minutes of administration of the dose

02.How long do the effects of this medicine last?

The amount of time for which this medicine remains active in the body is not clinically established

03.Is this a habit forming medicine?

No habit-forming tendencies were reported


04.Is it safe to consume alcohol while taking this medicine?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

05.Can this medicine be taken during pregnancy?

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

06.Can this medicine be taken while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Side Effects
Major & minor side effects
  • Shakiness in the legs, arms, hands, or feet
  • Sweating
  • Muscle stiffness
  • Tingling
  • Palpitations
  • Chest discomfort
  • Shortness of breath
  • Cough
  • Drowsiness
  • Dizziness
  • Headache
  • Stomach pain
  • Nausea and Vomiting
  • Diarrhoea
  • Skin rash and itching
When Not To Use
Allergy

This medicine is not recommended for use in patients with a known allergy to ambroxol, guaiphenesin, terbutaline, or any other inactive ingredients present along with these medicines

Gastric Ulceration

This medicine is not recommended for use in patients with a known history of gastric ulceration since it may worsen the patient's condition.

Stevens-Johnson Syndrome

This medicine is not recommended for use in patients with a known history of Stevens-Johnson syndrome which is a rare but serious disorder of the skin due to the increased risk of worsening of the patient's condition.

Dosage
Missed Dose

Take/Administer the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

WARNINGS
Warnings for special population


General warnings
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General Instructions

Use this medicine exactly as advised by your doctor. Do not use in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.